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Test Code 5HIAU 5 HIAA Urine

Important Note

Patients should abstain, if possible, from medications, over-the-counter drugs, and herbal remedies for at least 72 hours prior to the test. Foods rich in serotonin (avocados, bananas, eggplant, pineapple, plums, tomatoes, walnuts) and medications that may affect metabolism of serotonin must be avoided at least 72 hours before and during collection of urine for HIAA.

Use to diagnose carcinoid tumors and monitor disease.
 

Additional Codes

80420

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Specimen Type

Urine

Collection Volume

4.0 mL Random urine or send entire 24 hr collection to be aliquoted in lab.

Minimum Collection Volume

1.0 mL Random urine or  send entire 24 hr collection to be aliquoted in lab.

Collection Instructions

For 24 hour collecitons instruct the patient to void at 8:00 AM and discard the specimen.  Then collect all urine including the final specimen voided at the end of the 24-hour collection period, i.e., 8:00 AM the next morning.  Refrigerate during collection. Screw the lid on securely.  Specimens should be transported promptly to the Clinical Laboratory. In addition to two patient identifiers, container must be labelled with the date and time collection started, and date end time collection finished.  
 

Transport

Refrigerated

Rejection Criteria

Any sample other than urine.

Specimen Storage and Stability

Ambient: 48 hours; Refrigerated: 10 days; Frozen: 1 month
 

Turn Around Time

2-5 days

 

Lab Department

Referred Testing

Test Alias

5-HIAA; 5-OH-Indoleacetic Acid; Hydroxyindoleacetic Acid; Serotonin Metabolite; 5HIAA

 

CPT Coding

83497

EPIC Code

LAB352

Acceptable Collection Container

Random or 24 hour collection

Testing Volume

1.0 mL

Day(s) and Time(s) Performed

Sunday through Saturday

LOINC

Creatinine, Urine - per volume 2161-8
Creatinine, Urine - per 24h 2162-6
5-HIAA Urine Interpretation 44909-0
5-HIAA Urine - per 24h 1695-6
5-HIAA Urine - per volume 31203-3
5-HIAA Urine - ratio to CRT 44288-9
Total Volume 19153-6
Hours Collected 30211-7