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Test Code MUSCLE BIO General Information (Not orderable in LIS)--Muscle Biopsy

Specimen Type

Skeletal muscle

Collection Volume

4 × 2 × 2 cm

Collection Instructions

For routine histology, histochemistry, and electron microscopy, submit a piece of muscle which measures 4 × 2 × 2 cm. The muscle fibers should run along the longest dimension of the biopsy. Place on a piece of gauze moistened (not soaked) with normal saline. Specimens should be transported immediately to the Pathology Department located on the second floor of The Toledo Hospital. For biopsies referred to The Toledo Hospital, prepare as above. Place the muscle biopsy on gauze moistened with saline in a plastic, water-proof container. Place the container in a Styrofoam container packed with wet ice and transport within 8 hours to the Pathology laboratory. Label container with 2 patient identifiers (Full Name and DOB and/or MRN is acceptable),specimen source, and collection date.

Rejection Criteria

Improper fixative for special tests, unlabeled specimen containers, desiccated specimen.

Turn Around Time

48 hours to 3 weeks

Lab Department

Histology

Alias

Muscle Biopsy; Skeletal Muscle Biopsy;

Additional Information

The muscle biopsy should be selected from a moderately involved muscle on the basis of electromyography or other means of clinical evaluation. The muscle selected for biopsy should be on the contralateral side since electromyography produces histological changes which may mimic muscle disease. A detailed history is essential including current or recent use of steroids, familial history, clinical course, distribution and severity of the disease, laboratory findings, and results of electrophysiological studies. This form is available by calling the Pathology Office at 419-291-4370.

Day(s) and Time(s) Performed

Monday through Friday, 8:00am – 5:00pm