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Test Code MYBP Myelin Basic Protein, CSF

Specimen Type

Cerebrospinal fluid

Preferred Collection Container

CSFTUB4

Collection Volume

1 mL

Minimum Collection Volume

0.4 mL

Collection Instructions

Lumbar puncture should be performed within 5 days of onset of neurologic symptoms suggestive of multiple sclerosis. Place CSF in a plastic container and refrigerate.

Transport

Frozen

Rejection Criteria

Refrigerated specimens >14 days; Frozen specimens >30 days; Specimen at room temperature; Inadequate labeling; Improper collection; Insufficient volume. Not frozen.

Turn Around Time

1 – 4 days

Lab Department

Send Out

Aliases

MBP; Myelin Basic Protein;CSF, Myelin Basic Protein;Multiple Sclerosis (MS);Spinal Fluid, Myelin Basic Protein;

Acceptable Collection Container

Clean tube or container

Additional Information

Normal quantities of myelin basic protein are found when the MS patient is in remission, or when a very minute amount of nervous tissue is being demyelinated. MBP has also been detected in CSF of patients with CNS infarct, spondylolisthiasis, acute lumbar disc disease, after CNS trauma, pseudotumor cerebri, herpes encephalitis, and leukoencephalopathy associated with leukemia and neuropathy. MBP is cleared within two weeks after onset of symptoms.

Day(s) Performed

Monday, Wednesday, Friday

Reviewed

11/1/2013

Performing Laboratory

ARUP Laboratory—Send directly to
ARUP.